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Updated: Jul 16, 2026

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儿童NMDA受体脑炎的基于证据的诊断预测得分

Shimpei Matsuda1, Takayuki Mori2, Mariko Kasai2

  • 1Department of Brain & Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan; Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
|December 21, 2024
PubMed
概括

一个新的诊断评分有助于在儿童中早期检测抗N-甲基-D-酸盐受体脑炎 (NMDARE). 这个分数使用临床和实验室数据来改善诊断,并指导及时治疗以获得更好的结果.

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Encephalitis l: Introduction01:19

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Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...