2007-2021年丹麦角质细胞癌的流行,发病率和趋势:基于人口的注册研究
Anne Sofie Krogh Holdam1, Vibeke Koudahl2, Erik Frostberg3
1Department of Surgery, Plastic Surgery division, University Hospital of Southern Denmark, Vejle Hospital, Denmark; Institute of Regional Health Research, University of Southern Denmark, Denmark.
Cancer epidemiology
|December 21, 2024
概括
皮肤癌,基础细胞癌 (BCC) 和状细胞癌 (SCC) 的发病率在全球范围内正在上升. 这项研究揭示了年龄调整率的增加以及更大,更具侵入性的瘤的增加,这构成了未来的医疗保健挑战.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 皮细胞癌 (KC),包括基底细胞癌 (BCC) 和状细胞癌 (SCC),是一个日益严重的全球健康问题.
- 癌症的发病率越来越高,特别是需要手术的瘤,给医疗保健系统带来了巨大的负担.
- 了解年龄调整的发病率趋势对于未来有效管理KC至关重要.
研究的目的:
- 分析2007年至2021年丹麦BCC和SCC的年龄调整发病率趋势.
- 调查大型,侵入性 (≥T2) 和头瘤的趋势.
- 评估对医疗保健资源分配的影响.
主要方法:
- 针对BCC和SCC病例 (2007-2021) 的事件,利用了全国人口数据库.
- 根据年龄调整计算的发病率,标准化为2013年欧洲标准人口.
- 雇员joinpoint回归用于平均年度百分比变化估计和瘤特征的描述性统计数据.
主要成果:
- 确定了183,338个BCC和42,233个SCC病例.
- 观察到年龄调整后的发病率显著增加:BCC从每10万人中从252到338;SCC从每10万人中从49到104.
- 发现瘤≥T2和头部和部地区的瘤显著增加,在最后两年的研究中,SCC显著增加.
结论:
- 在2007年至2021年期间,BCC和SCC的年龄调整发病率显著增加.
- 同时,较高的T类瘤和敏感解剖部位的瘤同步增加.
- 随着KC的日益增加的外科手术负担,需要对医疗保健资源进行主动规划.
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