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在马的关节镜检查中,不使用赫西丁的酒精性消毒剂可用于马的关节镜检查

Y Nakamae¹, Y A Elce¹, M E Saab¹

¹Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Ave, Charlottetown Prince Edward Island, Canada C1A 4P3.

Journal of equine veterinary science

|December 21, 2024

概括

在关节镜手术期间,异醇 (IPA) 在马皮上的细菌减少与素酸盐 (CHG) 相比,在马皮上实现了类似的细菌减少. 这项研究支持IPA作为一种有效的替代品,用于马的手术现场准备.

科学领域:

兽医外科兽医外科兽医外科
抗菌药物的有效性抗菌药物的有效性
马类皮肤消毒剂马类皮肤消毒剂

背景情况:

赫西丁葡萄酸盐 (CHG) 是用于手术现场准备的标准消毒剂.
基于酒精的消毒剂在减少皮肤细菌方面已经显示出实验性有效性.
有限的临床数据存在,比较基于CHG和仅含酒精的协议在马术中.

研究的目的:

为了比较马皮的细菌计数 (CFU/mL) 立即和术后的减少,使用基于CHG的与基于异醇 (IPA) 的消毒剂.
为了测试这个假设,log10CFU/mL的减少不会在协议之间显著不同.
在临床环境中评估IPA无CHG在手术现场准备中的有效性.

主要方法:

六匹马经历了双边骨关节透视,四肢随机分配给CHG或IPA协议.
细菌样本在抗前 (T0),手术后 (T1) 和手术结束时 (T2) 立即收集.
殖民地形成单位 (CFU/mL) 被量化,日志转换,并使用ANOVA进行分析.

主要成果:

在CHG和IPA组之间立即 (T0-T1) 或持续 (T0-T2) log10CFU/mL减少没有显著差异 (P = 0.46,P = 0.42).
两种消毒剂方案都至少使细菌数量减少了2个日志.
限制包括小样本大小和缺乏遮.

结论:

基于异醇 (IPA) 的消毒剂在马类关节镜手术中有效用于手术准备.
在减少马皮上的细菌数量方面,IPA证明了与CHG相似的有效性.
需要进一步的临床研究来支持IPA作为可接受的CHG替代品.

关键词:

赫西丁 (Chlorhexidine) 是一种化学物质.马类动物马类动物异醇是什么意思?异醇是什么意思?手术性消毒剂可以用于手术.

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