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在CT导向热 Ablations期间的In Vivo温度映射:使用光谱CT的可行性证明

Andrea Ferrero¹, Thomas D Atwell¹, Brian T Welch¹

¹Department of Radiology, Mayo Clinic, Rochester, Minnesota.

Journal of vascular and interventional radiology : JVIR

|December 21, 2024

概括

这项研究使用计算机断层扫描 (CT) 信号绘制了临床剥离过程中的温度图. 该方法准确地可视化组织温度变化,帮助干预放射科医生.

科学领域:

医疗成像医学成像
生物物理学的生物物理.
干预性放射学干预性放射学

背景情况:

准确的温度监测对于有效的临床废除至关重要.
已知计算机断层扫描 (CT) 信号属性与温度相关.
开发非侵入性温度测绘技术是一个持续的挑战.

研究的目的:

开发和验证使用光谱计算机断层扫描 (CT) 进行临床切除期间温度映射的方法.
为了将CT信号变化与不同组织类型的温度变化相关联.
为了生成微波和冷洗的体内温度图.

主要方法:

具有特征的光谱CT信号依赖温度的软组织和脂肪模仿.
获得的光谱CT图像与光纤热传感器数据一起.
与局部温度相关的电子密度变化.
利用有效的原子数图像进行组织细分 (软组织,脂肪,骨).
应用衍生的电子密度-温度关系来生成温度图.

主要成果:

测量和验证了材料特定的热特性和温度依赖性.
有效的原子数成像使准确的组织细分成为可能.
在微波和冷却过程中生成体内温度图.
生成的温度图与干预放射科医生的预期保持一致.
观察脂肪/软组织接口的平滑温度过渡.

结论:

基于光谱CT的温度映射是临床废除的一种可行的技术.
该方法提供了准确的,非侵入性的温度可视化.
这种方法可以提高除程序的精度和安全性.

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