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Updated: Jun 4, 2025

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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SHIP-1通过抑制mTORC1活动来调节Tregs的分化和功能

Zuochen Du1,2,3,4,5, Jinzhi Wang1,2,3,4, Qian Liu6

  • 1Chongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.

Cellular and molecular life sciences : CMLS
|December 21, 2024
PubMed
概括

SHIP-1对于调节性T细胞 (Treg) 功能和稳定性至关重要. 在Tregs中删除SHIP-1会导致严重的自身免疫力和受损的抗瘤免疫力,突出显示SHIP-1是潜在的癌症治疗标.

关键词:
细胞代谢细胞代谢飞船1号的第一号船在Treg细胞中.在mTOROR中使用mTOR.

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