固定牙治疗对口腔健康和口腔微生物群的动态影响:一项前性研究
Mei Zhao1, Chaoran Yu1, Chengjun Su1
1School of Stomatology, Capital Medical University, Beijing, 100050, China.
BMC oral health
|December 21, 2024
概括
固定的正牙器具改变了口腔微生物群,尽管改善了卫生. 这项研究发现,经过六个月的治疗后,微生物多样性增加,潜在的致病性厌氧细菌增加.
科学领域:
- 口腔微生物学 口腔微生物学
- ортодонтическое 治疗 ортодонтическое 治疗
- 高通量测序的高通量测序
背景情况:
- 固定式正牙器件通常用于纠正牙缺陷.
- 这些设备可能会影响口腔卫生和口腔微生物群.
- 了解这些变化对于在治疗期间保持口腔健康至关重要.
研究的目的:
- 调查固定式正牙器具对口腔卫生的影响.
- 用高通量测序分析口腔微生物结构的变化.
- 评估在正牙患者中微生物多样性和丰度的变化.
主要方法:
- 一项前性临床研究,涉及45名接受固定牙科治疗的患者.
- 在治疗前和6个月后记录了口腔卫生参数和习惯.
- 唾液样本经历了16S rRNA基因测序和生物信息学分析.
主要成果:
- 观察到改善的口腔卫生:刷牙频率增加,斑块和碎片指数减少.
- 六个月后,唾液微生物多样性的显著增加.
- 发现了属级别的转变,增加了Firmicutes_C和Spirochaetota的丰度.
结论:
- 固定的正牙治疗诱导口腔微生物群结构的显著变化.
- 尽管口腔卫生得到改善,但无氧性和潜在的致病性细菌的增加被注意到.
- 这些微生物的变化可能会对牙科护理期间的口腔健康产生影响.
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