探索用于无血清媒体开发的成本降低策略
Jun Ping Quek1, Azra Anwar Gaffoor1, Yu Xuan Tan1
1Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Republic of Singapore.
NPJ science of food
|December 21, 2024
概括
开发具有成本效益的无血清介质 (SFM) 对可持续的养殖肉类生产至关重要. 本综述探讨了减少SFM费用的策略,包括优化生长因子和实施媒介回收以实现可扩展的细胞培养.
科学领域:
- 生物技术是生物技术.
- 食品科学 食品科学 食品科学
- 可持续农业 可持续农业
背景情况:
- 培养肉类生产为传统农业提供了一个可持续的替代方案,解决了粮食安全问题.
- 无血清介质 (SFM) 对于细胞培养至关重要,但却构成一个重要的成本障碍,往往超过运营费用的50%.
研究的目的:
- 审查和确定关键技术和战略,以降低培养肉类生产中无血清介质 (SFM) 的成本.
- 探索方法,使SFM更经济可行的大规模细胞培养.
主要方法:
- 对当前技术和研究的文献综述,用于培养肉类的SFM开发.
- 分析成本降低策略,重点关注增长因素,原材料和流程优化.
- 媒体回收和废物减少技术的探索.
主要成果:
- 确定了增长因素和重组蛋白质作为SFM的主要成本驱动因素.
- 突出了利用负担得起的原材料用于基底介质配方的潜力.
- 强调实施媒体回收和废物管理系统的经济效益.
结论:
- 降低SFM成本对于培养肉的商业可行性和可扩展性至关重要.
- 需要采用多方面的方法,结合优化的配方,价格合理的成分和高效的工艺.
- 在SFM领域进行进一步的研究和技术创新对于支持养殖肉类行业的增长至关重要.
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