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Updated: May 5, 2026

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
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In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis

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在患有类风湿性关节炎的患者中,从参考利图西马布过渡到生物类似利图西马布 (DRL_RI) 后,比较免疫性和安全性:一项随机,双盲,第三阶段研究

Narendra Maharaj1, Dharma Rao Uppada2, Naveen Reddy2

  • 1Clinical Development - Biologics, Dr. Reddy's Laboratories Ltd., Bachupally, Hyderabad, 500090, India. narendramaharaj@drreddys.com.

Arthritis research & therapy
|December 21, 2024
PubMed
概括

这项研究发现,将类风湿性关节炎患者从rituximab (RP/RMP) 转换为生物类似的DRL_RI导致了可比的免疫性和安全性. 过渡到DRL_RI证明了与继续使用参考产品相似的安全概况.

关键词:
生物类似物是什么意思免疫性 免疫性 免疫性类风湿性关节炎 类风湿性关节炎 类风湿性关节炎里图西马布 (Rituximab) 是一种药物.安全的安全的安全的安全的安全.切换 切换 切换 切换 切换过渡 过渡 过渡 过渡

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