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Updated: Jun 4, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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精神病遗传分析 生物型:共享的祖先调整的多基因风险和独特的基因组关联

Cuihua Xia1,2,3, Ney Alliey-Rodriguez2,4, Carol A Tamminga5

  • 1MOE Key Laboratory of Rare Pediatric Diseases & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, and Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Molecular psychiatry
|December 21, 2024
PubMed
概括

精神病生物型,由神经生物学定义,在祖先之间显示类似的祖先调整的多基因风险评分 (AAPRSs). 基因组分析确定了7个与神经通路相关的因果相关基因,这表明生物型特定的研究是有益的.

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