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Updated: Jun 4, 2025

Horizontal Hippocampal Slices of the Mouse Brain
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非电离子型NMDAR信号激活了Panx1,在海马中诱导P2X4R依赖的长期抑郁

Allison C Nielsen1, Connor L Anderson1, Carina Ens1

  • 1Department of Cell Biology & Anatomy, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

The Journal of physiology
|December 22, 2024
PubMed
概括

非离子型NMDA受体 (niNMDARs) 激活pannexin-1 (Panx1) 诱导长期抑郁症 (LTD) 通过链接谷氨酸和纯能途径. 这发生在短暂的NMDA受体抑制过程中,涉及ATP释放和P2X4受体.

关键词:
这就是ATPATPATP ATP.没有NMDAR,没有NMDAR.长期的抑郁症 长期的抑郁转基因转基因信号传输系统潘尼克辛‐1 的使用.纯激活的P2X4受体受体

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