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Updated: Jun 4, 2025

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
13:41

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Published on: March 8, 2012

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[16型HPV的E6和E7蛋白中的氨基酸替代模式:植物地理和进化]

E E Zelenova1,2,3, A A Karlsen4, D V Avdoshina5

  • 1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.

Molekuliarnaia biologiia
|December 22, 2024
PubMed
概括

高风险人类乳头瘤病毒 (HR HPV) E6和E7蛋白显示出地理变异性,具有与族群和HLA等位基因相关的独特氨基酸替代. 这影响了B细胞和T细胞表皮图的识别,影响了表皮图漂移和疫苗开发.

关键词:
B细胞的表观特征的T细胞表位.氨基酸替代物的氨基酸替代物共同差异分析的分析.人类乳头瘤病毒16型在蛋白质E6上.在蛋白质E7上.遗传学分析 遗传学分析

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