前庭训练对多发性硬化症患者认知功能的影响:一项随机对照试验
Moshera H Darwish1, Mohammed S El-Tamawy2, Manar E Ismail1
1Department of Physical Therapy for Neurology and Neurosurgery, Faculty for Physical Therapy, Cairo University, 12612, Egypt.
Multiple sclerosis and related disorders
|December 22, 2024
概括
在患有多发性硬化症 (PwMS) 的人群中,静止体训练显著改善了认知功能. 这种创新方法提高了PwMS中的特定认知测试和血清BDNF水平.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
背景情况:
- 认知功能障碍在患有多发性硬化症 (PwMS) 的人群中很常见,并且经常得到不充分的治疗.
- 中央前庭功能与PwMS的认知领域有关,无论残疾如何.
- 前庭训练对PwMS认知的影响以前没有被研究过.
研究的目的:
- 评估前庭训练在增强PwMS患者认知功能的有效性.
主要方法:
- 40名患有复发性缓解性多发性硬化症的PwMS被随机分为对照组 (有氧运动) 和研究组 (有氧运动加上前庭训练).
- 认知功能使用阿拉伯版本的MS简要国际认知评估 (BICAMS-A) 进行了评估.
- 血清脑源性神经营养因子 (BDNF) 水平被测量为生物标志物.
主要成果:
- 这两组在SDMT,CVLT-II,BVRT-R (BICAMS-A组件) 和血清BDNF治疗后显著改善.
- 与对照组相比,研究小组在CVLT-II,BVRT-R和血清BDNF中表现出显著更大的改善 (P <0.05).
结论:
- 垂体训练为PwMS的认知改善提供了一种有效和新的策略.
- 这些发现支持将前庭训练纳入多发性硬化症康复计划.
相关概念视频
The Vestibular System
39.3K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
39.3K
Equilibrium and Balance
4.4K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
4.4K


