在免疫检查点抑制剂的继发性IgLON5自身免疫
Christopher Itoh1, Grace Swart1, Erik St Louis1
1Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Journal of neuroimmunology
|December 22, 2024
概括
这项研究表明,免疫检查点抑制剂 (ICI) 可能会触发IgLON5自身免疫,特别是在患有高风险HLA单元型的患者中. 我们介绍了一个病例,患者在接受布罗利祖马布治疗后出现了这些症状.
科学领域:
- 神经免疫学 神经免疫学
- 自免疫神经学 自免疫神经学
背景情况:
- 自身免疫性IgLON5呈现出各种神经和睡眠症状,通常是渐进的.
- 它通常与特定的HLA单元类型有关,但通常不是神经瘤性或由免疫检查点抑制剂 (ICI) 诱导.
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