睡眠质量和发生的高血压
Zhihao Zheng1, Yanjun Song1, Zechen Liu1
1Cardiometabolic Medicine Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; State Key Laboratory of Cardiovascular Disease, Beijing, China; National Clinical Research Center for Cardiovascular Diseases, Beijing, China.
Revista espanola de cardiologia (English ed.)
|December 22, 2024
概括
睡眠质量不佳显著增加了高血压风险. 较长的睡眠时间可能会降低那些有健康或中间睡眠的人的风险. 这一发现即使在遗传倾向的情况下也是如此.
科学领域:
- 心血管健康 心血管健康
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 睡眠质量不佳是一个全球性公共卫生问题.
- 高血压是心血管疾病的主要危险因素.
- 了解睡眠等可修改的风险因素对于预防至关重要.
研究的目的:
- 调查睡眠质量与患新发高血压的风险之间的关联.
- 检查睡眠时间与高血压风险相关的作用.
- 评估这种关联是否受高血压遗传倾向的影响.
主要方法:
- 分析了两个大型队列:英国生物库 (UKB) 和英国老化纵向研究 (ELSA).
- 包括没有基线高血压的成年人 (UKB: 284,250; ELSA: 6,104).
- 睡眠质量通过问卷进行评估;睡眠时间根据自我报告的小时.
主要成果:
- 睡眠质量差与UKB (HR, 1.277) 和ELSA (HR, 1.264) 队列中高血压风险更高显著相关.
- 延长睡眠时间与中等或健康睡眠质量的人群中高血压风险降低相关.
- 睡眠不足和高血压风险增加之间的联系仍然很重要,无论遗传敏感性如何.
结论:
- 睡眠质量差是高血压风险升高的独立风险因素,即使考虑到遗传倾向.
- 优化睡眠时间,特别是对于睡眠质量中等或健康的人来说,可以减轻高血压风险.
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