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Collection, Expansion, and Differentiation of Primary Human Nasal Epithelial Cell Models for Quantification of Cilia Beat Frequency
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锡纳罗皮克林通过抑制SERCA来增加人类气道上皮细胞中的[Ca2+]和脉跳动频率

Nobuhisa Todo1, Shigekuni Hosogi1, Seikou Nakamura2

  • 1Laboratory of Clinical and Translational Physiology, Kyoto Pharmaceutical University.

Biological & pharmaceutical bulletin
|December 22, 2024
PubMed
概括

菜提取物cynaropricin通过增加细胞内cAMP和Ca2+水平来增强粘膜清除 (MCC). 这种化合物增强了纤毛节拍频率 (CBF),为呼吸系统健康带来了潜在的益处.

关键词:
节拍的频率 节拍的频率锡纳罗皮克林 (Cynaropicrin) 是一种葡萄素.细胞内Ca2+度的度.细胞内cAMP度的度萨尔科内质网膜中的Ca2+-ATPase酶.

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