了解肠道微生物群的复杂功能:它对肥胖病变的产生及其影响:全面的综述
Aref Yarahmadi1, Hamed Afkhami2,3,4, Ali Javadi5
1Department of Biology, Khorramabad Branch, Islamic Azad University, Khorramabad, Iran.
Diabetology & metabolic syndrome
|December 22, 2024
概括
肠道微生物群通过影响新陈代谢和食欲,显著影响肥胖. 针对肠道细菌的策略,包括益生菌和饮食,显示出对体重管理和代谢健康改善的希望.
科学领域:
- 微生物组研究的研究.
- 代谢障碍 代谢障碍 代谢障碍
- 肥胖科学 肥胖科学
背景情况:
- 肥胖是多因素的,涉及遗传学,环境和肠道微生物群.
- 肠道微生物组对于肠道健康,新陈代谢和能量平衡至关重要.
- 微生物组不平衡 (失生症) 导致食欲增加和代谢障碍,助长肥胖.
研究的目的:
- 审查肠道微生物群在肥胖中的多方面的作用.
- 探索肠道微生物群变化与儿童肥胖之间的联系.
- 总结针对肠道微生物组的肥胖现有和潜在的治疗策略.
主要方法:
- 这是编译现有科学知识的叙事概述.
- 该评论综合了关于肠道微生物群在肥胖中的作用的信息.
- 它研究了各种治疗干预措施及其对微生物平衡的影响.
主要成果:
- 失生症与食欲增加和代谢障碍有关,有助于肥胖.
- 儿童肥胖与肠道细菌的特定变化有关,包括促炎型的增加.
- 目前的治疗策略如益生菌,益生菌,共生菌,FMT,饮食改变和体育活动显示出对肥胖管理的潜力.
结论:
- 肠道微生物群在肥胖的发展和进展中起着复杂的作用.
- 准肠道微生物组为肥胖和相关代谢问题提供了有希望的治疗途径.
- 需要进行进一步的临床试验,以优化基于微生物组的干预措施,以减肥和长期有效.
更多相关视频
相关概念视频
Hormonal Regulation
43.1K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
43.1K
Obesity
374
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
374
Anatomy of the Intestines
71.3K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.3K
Irritable Bowel Syndrome I: Introduction
244
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
244
What is Monogastric Digestion?
70.5K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
70.5K
Bacterial Flora of the Large Intestine
377
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
377


