SARS-CoV-2对男性性功能的影响 更新评论
Radheshyam Pal1, Prashant Kumar2, Ekta Khare3
1Department of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences & Research, Durgapur, 713212, West Bengal, India.
Infectious disorders drug targets
|December 23, 2024
概括
严重的COVID-19 (SARS-CoV-2) 影响男性生殖健康,可能导致不孕症和性功能障碍. 研究审查了这些影响精子和激素的男性从病毒中恢复的生产.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 病毒学 病毒学
- 安德罗学与人类学
背景情况:
- 严重急性呼吸系统综合征-冠状病毒2 (SARS-CoV-2) 已经造成了具有显著死亡率的全球大流行.
- 存在着显著的性别差异,男性的死亡率和疾病严重程度更高.
- 男性生殖系统可能对SARS-CoV-2感染具有独特的脆弱性.
研究的目的:
- 审查SARS-CoV-2对男性生殖健康的影响.
- 总结关于男性生殖组织中病毒存在的发现.
- 讨论对生育能力和性功能的潜在长期后果.
主要方法:
- 关于SARS-CoV-2和男性生殖健康现有研究的文献综述.
- 对调查丸和阴茎组织中病毒存在的研究进行分析.
- 检查报告生殖细胞和莱迪格细胞枯竭的研究.
主要成果:
- 在现生和已故的男性生殖组织中检测到SARS-CoV-2病毒颗粒.
- 感染可以导致生殖细胞和莱迪格细胞的枯竭,影响精子生产和荷尔蒙释放.
- 虽然性传播率较低,但中度至重度的COVID-19可能会导致耳炎和勃起功能障碍.
结论:
- SARS-CoV-2对男性生殖健康构成风险,可能导致不孕症和性功能障碍.
- 需要继续进行研究,才能充分理解人工生殖对人工生殖的长期影响和影响.
- 在管理SARS-CoV-2感染时,应考虑男性生殖健康.
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