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Updated: Jun 4, 2025

A New Approach for the Comparative Analysis of Multiprotein Complexes Based on 15N Metabolic Labeling and Quantitative Mass Spectrometry
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深海CYP51的独特结构特征与高压适应有关

Tatiana Y Hargrove1, David C Lamb2, Zdzislaw Wawrzak3

  • 1Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.

Research square
|December 23, 2024
PubMed
概括

深海鱼和人体醇14α-脱甲基酶 (CYP51s) 晶体结构显示出独特的特征. 这些结构洞察力解释了酶的灵活性,催化效率和适应深海环境,超过了人工智能预测.

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