重温肥胖悖论:肥胖是否仍然是高并发症负担或高复杂性手术患者的保护因素?
Hyo Jin Son1, Denise W Gee2, David Gomez3
1From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
概括
肥胖悖论可能不适用于所有手术患者. 高度的程序复杂性和并发症负担降低了肥胖对术后死亡率的保护作用.
科学领域:
- 手术成果研究的研究结果.
- 肥胖药物 肥胖药物 肥胖药物
- 公共卫生 公共卫生
背景情况:
- "肥胖悖论"表明,尽管存在相关的健康风险,但肥胖患者的术后结果得到了改善.
- 有限的研究存在于程序复杂性和并发症如何影响这种关系.
研究的目的:
- 调查肥胖和术后死亡率之间的关联.
- 检查程序复杂性和并发症负担对这种关系的影响.
主要方法:
- 使用2016-2019年国家外科质量改进计划数据库进行的观察性研究.
- 分析了3,085,582名接受重大手术的成年患者.
- 风险调整的多变量回归和受限立方线模型,以评估BMI对30天死亡率的影响,按程序复杂性和并发症负担分层 (修改的查尔森并发症指数).
主要成果:
- 在整体队列中观察到BMI和死亡率之间的反向J形关系,支持肥胖悖论.
- 在接受高复杂性手术的肥胖患者中,与正常BMI患者相比,死亡率没有显著差异.
- 同样,肥胖悖论趋势在高并发症负担的患者中消失了.
结论:
- 肥胖悖论存在于大多数成年手术患者中.
- 然而,肥胖对术后死亡率的保护作用随着程序复杂性和并发症负担的增加而减少.
更多相关视频
05:30Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
Published on: February 14, 2025
731
08:30Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
Published on: March 15, 2018
14.1K
相关概念视频
Obesity
374
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
374
Stress Prevention and Stress Management Techniques IV
26
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
26
Methods of Documentation VI: Case Management Model
559
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
For example, a patient with a chronic...
559
Strategies for Assessing and Addressing Confounding
83
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
83
Binge Eating Disorders
48
Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
48
Bulimia Nervosa
46
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
46
