关于艾森门格综合征的最新情况 - 病理生理学审查和风险评估和管理方面的最新进展
Ranjan Banerjee1, Alexander R Opotowsky1
1The Cincinnati Adult Congenital Heart Disease Program, Heart Institute, Cincinnati Children's Hospital, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
International journal of cardiology. Congenital heart disease
|December 23, 2024
概括
由于早期干预,艾森门格综合征 (ES) 是先天性心脏病的并发症,正在下降. 针对疾病的治疗方法可能会改善生活质量和生存率,但死亡率仍然很高.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 遗传学 是一个遗传学.
背景情况:
- 艾森门格综合征 (ES) 源于先天性心脏病 (CHD) 中长期存在的左向右转移,导致肺血管重塑和高血压.
- ES是一种多系统性疾病,具有多种表现,严重受到慢性低氧化血的影响.
研究的目的:
- 审查艾森门格综合征的病理生理学,风险分层和不断变化的管理策略.
- 要突出最近在ES的药理和外科干预方面的进展.
主要方法:
- 关于艾森门格综合征的现有文献的审查.
- 对心脏病早期诊断和干预对ES发病率的影响分析.
- 在ES管理中对疾病向疗法 (DTT) 的评估.
主要成果:
- 由于早期的CHD干预,ES的发病率在先进的儿科心脏护理区域下降.
- 针对疾病的治疗与改善ES患者的生活质量和潜在的更好的生存率有关.
- 尽管治疗方面取得了进展,心力衰竭仍然是ES患者死亡的主要原因.
结论:
- 虽然早期诊断和新疗法改善了结果,但艾森门格综合征仍然是一个复杂的疾病,存在重大知识差距.
- 需要进一步的研究来解决风险分层和风险管理的剩余挑战,以减少ES死亡率.
相关概念视频
Esophageal Varices-II: Clinical Features and Management
46
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
46
Barrett Esophagus-II: Clinical Manifestations and Management
103
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
103
Esophageal Perforation-II: Clinical Manifestations and Management
44
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
44
Esophageal Strictures-II: Clinical Features and Management
46
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
46
Gastroesophageal Reflux Disease II: Clinical Features and Management
54
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
54
Esophageal Varices-I: Introduction
72
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
72


