牛奶的气味和味道对早产新生儿养参数的影响:更新的元分析
Sarah Alenezi1, Manal Aldaihani1, Sabah Alqabandi1
1Department of Medicine and Surgery, Kuwait Institute for Medical Specializations, Kuwait City, KWT.
Cureus
|December 23, 2024
概括
嗅觉和味觉干预显著缩短了早产婴儿实现口服养的时间. 这项研究发现,这些感官干预对早产婴儿有益,减少了食时间,但没有影响其他临床措施.
科学领域:
- 新生儿医学 新生儿医学
- 发育儿科 发育儿科
- 感官科学 感官科学
背景情况:
- 嗅觉和味觉刺激与早产婴儿的积极食结果有关.
- 感官干预对早产婴儿过渡到口服食的具体影响需要进一步澄清.
研究的目的:
- 评估嗅觉和味觉干预措施在改善早产婴儿临床结果方面的有效性.
- 为了确定感官干预对新生儿口服养时间的影响.
主要方法:
- 一项对12项随机对照试验 (RCT) 的系统综述和元分析,涉及1,638名早产婴儿 (妊娠年龄<34周).
- 在主要的数据库 (PubMed,Scopus,Web of Science,Cochrane) 中进行了搜索.
- 使用Cochrane的偏差风险工具 (版本2) 评估研究质量;使用随机效应模型分析结果.
主要成果:
- 嗅觉和味觉干预显著减少了1.37天 (95% CI [-2.26, -0.48],p < 0.001) 的口服养时间.
- 对于次要结果没有发现显著差异,包括完全肠道养的时间,住院时间或感染率.
- 根据出生体重,暴露类型和样本大小的亚组分析,结果保持一致.
结论:
- 嗅觉和味觉干预措施有效地加速了早产婴儿转向口服养的过程.
- 虽然这些干预措施对养时间有好处,但与标准护理相比,这些干预措施并没有显著改变其他临床结果.
- 建议进行进一步的大规模RCT和长期后续研究,以充分阐明益处.
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