一个用于对神经群体动态非线性模型应用振荡和同步的最佳控制框架
Lena Salfenmoser1, Klaus Obermayer1,2
1Institute of Software Engineering and Theoretical Computer Science, Technische Universitaet Berlin, Berlin, Germany.
我们适应了最佳控制理论 (OCT) 来管理神经网络的振荡和同步,而不需要精确的目标路径. 这种新方法为控制复杂的大脑动态提供了灵活性.
科学领域:
- 计算神经科学是一种神经科学.
- 系统神经科学 系统神经科学
- 控制理论 控制理论
背景情况:
- 最佳控制理论 (OCT) 用于计算动态系统的高效刺激.
- 标准的OCT需要一个明确的参考轨迹,这对振荡目标来说是有限制的.
- 控制神经群体中的振荡和网络同步对于理解大脑功能至关重要.
研究的目的:
- 在神经人口模型中调整非线性OCT以控制振荡和网络同步.
- 引入针对振荡和同步而没有参考轨迹的新型成本函数.
- 将这些方法应用于各种神经模型和控制任务.
主要方法:
- 为OCT开发了三个替代成本函数,以振荡和同步为目标.
- 将这些函数应用于单节点和网络模型 (Wilson-Cowan,整合和发射神经元).
- 计算机控制策略用于驱动振荡,状态切换,相位控制和 (非) 同步.
主要成果:
- 在使用无轨道成本函数的神经模型中成功控制了振荡和同步.
- 在状态切换控制信号中观察到翻译不变性.
- 根据所使用的成本函数,发现了不同的控制策略来实现脱同步.
结论:
- 开发的方法提供了一个工具箱,用于将振荡现象纳入非线性OCT.
- 这种方法可以控制神经动态,而无需指定精确的参考轨迹.
- 为了获得最佳的结果,需要对特定任务的参数进行调整.
更多相关视频
10:46Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
Published on: June 22, 2017
05:59Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis
Published on: October 6, 2023
相关概念视频
Damped Oscillations
Although friction and other non-conservative...
Oscillations about an Equilibrium Position
Linear time-invariant Systems
The input-output behavior of an LTI system can be fully defined by its response to an impulsive excitation at its input. Once this impulse response is known, the system's reaction to any other input can be...
BIBO stability of continuous and discrete -time systems
To determine the BIBO stability, the convolution integral is utilized when a bounded continuous-time input is applied to a Linear Time-Invariant (LTI) system....
Forced Oscillations
Propagation of Action Potentials
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
