孕产妇接触农药和出生缺陷的风险:中国的一项基于人口的横截面研究
Fangfang Liu1, Xiayang Li2, Jie Chen2
1Department of Stomatology, Xi'an Central Hospital, Xi'an, Shaanxi, China.
Frontiers in public health
|December 23, 2024
概括
孕妇在怀孕前和早期接触农药显著增加了出生缺陷的风险,特别是心血管问题. 在这个关键时期避免使用农药对于婴儿健康至关重要.
科学领域:
- 环境健康 环境健康
- 生殖流行病学 生殖流行病学
- 甲状腺学 甲状腺学
背景情况:
- 孕前期接触农药是产生不良分娩后果的潜在危险因素.
- 了解这种关联对于公共卫生干预至关重要.
研究的目的:
- 调查孕期期间母亲暴露于农药和出生缺陷发生率之间的联系.
- 为了确定与农药暴露相关的特定类型的出生缺陷.
主要方法:
- 这项调查是对中国西省的29,204名妇女进行的,这些妇女在2010年至2013年之间生了婴儿.
- 使用国际疾病分类第十次修订 (ICD-10) 诊断的出生缺陷.
- 一般估计方程 (GEE) 双项回归模型用于分析关联,调整共变量.
主要成果:
- 农药暴露组 (737.46/10,000) 与对照组 (186.04/10,000) 的出生缺陷发生率增加.
- 母亲接触农药与整体出生缺陷的风险增加2.39倍有关.
- 暴露的母亲患心血管系统缺陷的风险增加了3.14倍.
结论:
- 孕产妇暴露于周围受精的农药与更高的出生缺陷风险有关,包括心血管缺陷.
- 建议从怀孕前三个月到头三个月避免接触农药,以减少出生缺陷的风险.
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