在急性缺血性中风患者内血管血栓切除术后死亡率的特征
Jian Wang1, Qian Liu1, Fayun Hu1
1Department of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Clinical interventions in aging
|December 23, 2024
概括
对于急性缺血性中风 (AIS) 的内血管血栓切除术 (EVT) 后的死亡率通常是由于恶性脑 (MCE),肺炎或症状性内出血 (sICH). 了解这些原因有助于改善患者的治疗结果和EVT后护理.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 干预心脏病学 干预心脏病学
背景情况:
- 血管内血栓切除术 (EVT) 已经推进了急性缺血性中风 (AIS) 治疗.
- 然而,EVT后的死亡率仍然令人担忧,最近的现实数据有限.
- 了解最近的死亡率模式对于优化EVT协议至关重要.
研究的目的:
- 调查AIS患者在EVT后30天内死亡的主要原因.
- 确定与不同死亡原因相关的临床特征.
- 提供有关EVT相关死亡的最新流行病学数据.
主要方法:
- 这是一项多中心的回顾性研究,对721名AIS患者进行了研究,这些患者在EVT后死亡.
- 数据来自中国四川省33家医院 (2019年1月 - 2022年9月).
- 分析的重点是死亡原因和相关的临床因素.
主要成果:
- 主要死亡原因:恶性脑 (MCE) (50.6%),肺炎 (25%) 和症状性内出血 (sICH) (13%).
- 在前部循环中风和EVT后早期死亡中,MCE占主导地位;肺炎随着时间的推移和后部循环中风增加.
- 与MCE相关的因素包括大血管封闭和低再输血率;与肺炎相关的晚年;与手术并发症相关的sICH.
结论:
- 恶性脑,肺炎和症状性脑内出血是EVT后死亡的主要原因.
- 不成功的再输血与MCE有关;程序并发症和操作员经验与SICH有关.
- 肺炎是晚期死亡的一个重要原因,受到EVT后管理的影响.
相关概念视频
Venous Thrombosis III: Interprofessional Care
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Transient Ischemic Attack l: Introduction
A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...


