与癌性胆囊炎相关的危险因素:来自印度东部的队列研究
Karthikarajam V1, Nalubolu Pushpaketu1, Samit Badhai1
1Department of General Surgery, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Cureus
|December 23, 2024
概括
癌性胆囊炎 (GC) 的危险因素包括年龄较大,男性性别,并发症以及特定的实验室和成像发现. 早期识别这些因素对于及时干预和改善患者结果至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 癌性胆囊炎 (GC) 是一个重大的临床挑战,具有高死亡风险,需要紧急干预.
- 早期识别风险因素对于停止炎症过程和预防严重并发症至关重要.
研究的目的:
- 评估人口统计学,临床和成像学因素,以便在急性胆囊炎患者中早期预测癌变.
主要方法:
- 一项前性研究涉及340名被诊断患有急性胆囊炎的成年患者.
- 数据分析包括使用SPSS软件进行描述性统计,奇平方测试和未配对的t测试.
- 统计学意义是通过小于0.05.5的p值来确定的.
主要成果:
- 在340名患者中,7.9%的患者进展为GC,主要是男性 (81.5%) 和51至70岁 (55.5%) 的人.
- 伴随性疾病 (糖尿病,冠状动脉疾病),发烧和吐与GC显著相关.
- 在GC患者中观察到升高的WBC, bilirubin,SGOT, SGPT,ALP,以及特定的超声检测结果 (不对称的GB壁,内膜,周围囊收集). CECT显示了74.1%的灵敏度和85.6%的特异性.
结论:
- 年龄较大,男性性别,高水平的实验室标志物和特定的成像特征是预测GC的关键指标.
- 综合人口,临床和成像数据的综合方法对于有效的预测和治疗指导至关重要.
相关概念视频
01:22Appendicitis-I: Introduction
88
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
88
01:29Chronic Pancreatitis II: Collaborative Care
70
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
70
01:24Chronic Pancreatitis I: Introduction
71
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
71
01:17Chronic Bowel Disorders: Introduction
386
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
386
01:23Gastritis III: Clinical Manifestations and Management
153
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
153
01:24Esophageal Varices-I: Introduction
72
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
72