多模式治疗练习及其在缓解化疗诱导的外周神经病变中的作用:对患者结果的纵向研究
Trupti Yadav1, G Varadharajulu2, Rashmi Gudur3
1Department of Oncologic Physiotherapy, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Cureus
|December 23, 2024
概括
与标准物理治疗相比,多式运动计划显著改善了化疗诱导的周围神经病变 (CIPN) 症状和日常生活技能. 这种方法提供了一种更有效的方式来管理CIPN,并提高癌症患者的生活质量.
科学领域:
- 神经学 神经学
- 在瘤学瘤学.
- 物理疗法物理治疗
背景情况:
- 化疗诱导的周围神经病变 (CIPN) 是癌症治疗的常见和衰弱的副作用.
- 现有的CIPN治疗方法,如标准物理治疗,在症状管理和功能恢复方面具有有限的有效性.
研究的目的:
- 为了比较多式运动计划与标准物理治疗治疗CIPN症状的有效性.
- 评估这些干预措施对神经病症评分和日常生活工具活动的影响.
主要方法:
- 78名患有CIPN (2或3级) 的参与者被随机分为两组:多式运动计划 (A组) 或标准物理治疗 (B组).
- 神经病症严重程度使用修改后的总神经病症评分 (mTNS) 进行评估,功能状态通过劳顿仪器活动日常生活量表 (L-IADL) 进行预干预和后干预测量.
主要成果:
- 与B组 (14.98至13.66,p=0.00116) 相比,A组的mTNS得分 (14.68至7.03,p<0.0001) 在统计学上显著下降.
- 在A组 (7.54至11.23,p<0.0001) 中,L-IADL得分的改善明显大于B组 (5.51至7.35,p=0.001).
- 这两种结果措施都显示了干预后两组的显著改善,多式联动运动组的结果优越.
结论:
- 多模式炼计划在缓解CIPN症状和改善功能结果方面优于标准物理治疗.
- 综合性,多式联动性运动干预措施有望提高患有CIPN的癌症患者的生活质量.
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