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饮食中的B族维生素会影响Drosophila melanogaster对饮食酵母的偏好

Dean B Peterson¹, John Chaston¹, Andrew T Call¹

¹Department of Plant and Wildlife Sciences, Brigham Young University, Provo, UT, United States.

microPublication biology

|December 23, 2024

概括

肠道细菌Acetobacter fabarum会影响果酵母菌的偏好. 胺和其他B族维生素受到细菌新陈代谢的影响,在这种饮食选择中起着关键作用.

科学领域:

微生物学微生物学
营养科学营养科学
动物行为动物行为

背景情况:

肠道微生物群显著影响宿主的饮食偏好.
已知微生物对*Drosophila melanogaster*对酵母的饮食偏好 (DPY) 的影响.
之前的研究发现了影响DPY的*Acetobacter fabarum*突变,其中一些与胺代谢有关.

研究的目的:

为了研究胺在调节 *Drosophila melanogaster* DPY 的直接作用.
要确定胺补充剂是否会影响与特定*Acetobacter fabarum*突变分子单关联的中的DPY.

主要方法:

*Drosophila melanogaster*与野生类型和突变的 *Acetobacter fabarum* 菌株的单联.
用胺和其他B族维生素进行食补充剂实验.
在对微生物和营养操纵的反应中量化DPY.

主要成果:

提氨酸和其他B族维生素被证明可以直接影响*D. melanogaster*DPY.
不同的*Acetobacter fabarum*突变体对胺补充剂表现出不同的DPY反应.
由肠道细菌调解的特定营养因素被确定为DPY的关键影响者.

结论:

胺是一种关键的营养效应因子,影响D. melanogaster对酵母的饮食偏好.
肠道微生物群代谢和宿主营养之间的相互作用塑造宿主养行为.
这项研究阐明了微生物代谢物调节宿主饮食选择的特定机制.

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