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Updated: Jun 4, 2025

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在子宫内接触双A和S的环境相关剂量会破坏跨代的生殖细胞编程,由单核多基因组解决

Liang Zhao1,2, Mingxin Shi1, Sarayut Winuthayanon3

  • 1School of Molecular Biosciences, Center for Reproductive Biology, Washington State University, 1770 NE Stadium Way, Pullman, WA, 99164, USA.

bioRxiv : the preprint server for biology
|December 23, 2024
PubMed
概括

产前暴露于双A (BPA) 和BPS,通过改变生殖细胞表观遗传学,扰乱了老鼠几代的精子数量. 染色体可访问性和基因表达的这些变化至少持续了三代.

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