成年人的部分异常肺静脉回归:对肺高血压的洞察
Nour Rahnama1, Linda Kubangumusu2, Agnes Pasquet1
1Division of Cardiology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
部分异常肺静脉回归 (PAPVR) 影响0.2%的患者,可能导致肺动脉高血压 (PAH). 对偶发的PAPVR病例的后续行动不足是常见的,这突显了需要更好的管理策略的需要.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
背景情况:
- 部分异常肺静脉回归 (PAPVR) 是一种罕见的先天性心脏病.
- PAPVR可能导致严重的心血管并发症,包括肺动脉高血压 (PAH).
- 了解PAPVR的患病率和长期影响对于患者管理至关重要.
研究的目的:
- 为了确定成年人中PAPVR的流行率.
- 评估偶然诊断的PAPVR的随访率.
- 研究体积和压力过载对右心室 (RV) 的影响,并确定PAPVR患者中PAH的预测因子.
主要方法:
- 通过胸部计算机断层扫描 (CT) 报告识别的50名成人PAPVR患者的回顾性分析.
- 跨胸腔回声心脏成像和多切片成像用于心脏评估.
- 评估右心体积,RV功能,以及PAH的存在.
主要成果:
- 发现PAPVR患病率为0.2% (23/13,606个CT报告).
- 54%偶然诊断的PAPVR患者缺乏心脏随访.
- 14%的PAPVR患者患有PAH,Qp/Qs比率是唯一的预测因素.
- PAPVR诱导的体积过载增加了RV体积,而PAH诱导的压力过载损害了RV功能.
结论:
- PAPVR不常见,但具有风险,包括PAH,需要勤奋的随访.
- Qp/Qs比率是PAPVR患者发展PAH的一个关键预测指标.
- 在RV上区分体积和压力过载的影响对于了解疾病进展至关重要.
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