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在没有痴呆症的人群中,地中海饮食和大脑功能连接

Efstratios Karavasilis¹, Vasileios Balomenos^2,3, Foteini Christidi^4,5

¹Medical Physics Lab, Scholl of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

Frontiers in neuroimaging

|December 23, 2024

概括

在没有痴呆症的老年人中,更高的地中海饮食 (MeDi) 坚持与更好的大脑功能连接 (FC) 有关. 这表明MeDi可能支持认知健康和大脑衰老.

科学领域:

神经科学是一个神经科学.
营养科学营养科学
老年学是指老年学的学科.

背景情况:

饮食等生活方式因素会影响认知功能和大脑的测量.
在非痴呆人口中,地中海饮食 (MeDi) 与功能连接 (FC) 之间的关系仍未得到充分探索.

研究的目的:

调查在没有痴呆症的个体中遵守地中海饮食 (MeDi) 和休息状态功能连接 (rs-FC) 之间的关联.

主要方法:

105名没有痴呆症的成年人 (平均年龄63岁) 接受了休息状态的fMRI.
通过24小时回忆评估了饮食摄入量;使用MedDietScore量化了MeDi坚持.
多变量线性回归分析了MedDietScore和rs-FC之间的关联.

主要成果:

发现MedDietScore和rs-FC之间在前额和前额头部区域之间存在显著的关联.
积极的关联将MedDietScore与中间前额叶皮层和左侧后中心/上边缘回转之间FC联系起来.
负面关联将MedDietScore与中间视觉和右后旋之间的FC联系起来.

结论:

较高的 MeDi 坚持与对认知过程至关重要的大脑区域的 rs-FC 变化相关.
这些发现支持MeDi在大脑衰老中的有益作用,并表明它对老年人口的潜在临床影响.
休息状态fMRI显示为营养神经科学中的生物标志物,用于评估大脑衰老.

关键词:

老化的老化衰老的老化生物标志物生物标志物功能连接性的功能连接性地中海饮食地中海饮食 rs-fMRI 是一个

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