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在初级保健和社区药房之间改善质子抑制剂坚持干预:干预前后研究
María Puig-Moltó1, Blanca Lumbreras1,2, Elsa López-Pintor2,3
1Department of Public Health, History of Science and Gynecology, Miguel Hernandez University, San Juan de Alicante, Spain.
对质子抑制剂 (PPI) 治疗的不良坚持往往导致治疗失败. 在社区药房进行的一项合作性药物干预显著改善了患者的药物坚持和症状缓解.
科学领域:
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 质子抑制剂 (PPI) 治疗对于管理上部胃肠道症状至关重要.
- 患者对PPI的不良坚持往往导致治疗失败.
- 社区药房是患者干预的可访问点.
研究的目的:
- 评估药物干预的有效性.
- 评估初级保健和社区药房之间的合作模式.
- 为了提高PPI在患有上部胃肠道症状的患者的坚持.
主要方法:
- 在西班牙社区药房进行了干预前后研究.
- 莫里斯基药物坚持度表 (MMAS-4) 评估了基线时的坚持.
- 胃食道逆流性疾病影响量 (GIS) 测量了干预后的结果.
主要成果:
- 超过一半的患者 (50.7%) 最初不坚持PPI.
- 在68.5%的不坚持治疗的患者中,提供了药物干预.
- 整体GIS得分在干预后显著改善 (p < 0.001).
结论:
- 药物干预对缓解症状和生活质量产生了积极的影响.
- 初级保健和药房之间的协作模式是有效的.
- 这突显了专业制药服务在改善PPI遵守方面的价值.
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