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新西兰眼科药物中的过敏原
Carneshika Bernadette Hettiaratchi1,2,3, Harriet Kennedy1,3
1Department of Dermatology, Auckland City Hospital, Te Whatu Ora Health, New Zealand.
The Australasian journal of dermatology
|December 23, 2024
概括
大多数眼滴含有常见的过敏原,如化,这可能导致眼过敏接触性皮肤炎 (ACD). 使用本地数据定期更新使用本地数据进行补丁测试系列对于准确诊断ACD至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 皮肤病学 皮肤病学
- 过敏学 过敏学
背景情况:
- 由眼科药物引起的眼过敏接触性皮肤炎 (ACD) 经常被低估,导致患者的治疗结果低于最佳.
- 眼ACD的准确诊断依赖于眼药中的潜在过敏原的最新知识.
- 对眼科产品中普遍存在的过敏原的全面了解对于有效的临床管理至关重要.
研究的目的:
- 在新西兰可用的眼科药物中识别和目录存在的过敏原.
- 评估当前眼部制剂中新西兰基线系列扩展 (NZBSE) 过敏原的流行率.
- 为更新补丁测试系列和改善ACD诊断提供数据.
主要方法:
- 在2023年10月,对新西兰处方药和非处方眼科药进行了横截面审查.
- 分析了产品数据表中的成分列表,不包括未经批准或不可用的产品.
- 用料按功能分类,并记录了NZBSE过敏原的存在.
主要成果:
- 在分析的67种局部药物 (115种配方) 中,58%含有至少一种NZBSE过敏原.
- 化是最常见的过敏原 (48%),其次是基醇 (6%),兰诺林 (4%) 和 parabens (4%).
- 其他确定的过敏原包括凯因麻醉剂 (2%),氨酸硫酸 (2%) 和cetearyl酒精 (1%).
结论:
- 眼科制剂中的很大一部分含有已知的过敏原,可以触发ACD.
- 补丁测试系列应以当地数据为基础,并定期更新以确保诊断准确性.
- 测试患者自己的眼科产品对于识别引起过敏的过敏原至关重要.
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