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在中国儿科中结桃体切除术后的出血风险:一个多中心,前性,观察性队列研究
Hongming Xu1, Shuyao Qiu2, Jinxia Wang3
1Department of Otorhinolaryngology Head and Neck Surgery, School of Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, No.355, Luding Road, Shanghai, 200062, China.
概括
结合性桃切除术后出血 (PCTH) 在中国1.99%的儿科患者中发生. 关键的危险因素包括异常凝血和较长的手术,同时观察到出血率的区域差异.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 儿科手术 儿科手术
- 血液研究研究出血.
背景情况:
- 结合性桃切除术是儿童患者广泛使用的手术程序.
- 桃体切除术后出血 (PTH) 是一种已知的并发症,需要研究特定的技术,如结.
- 了解儿科人群中结合性桃体切除术后出血 (PCTH) 的发生率和危险因素对于改善患者安全至关重要.
研究的目的:
- 为了确定中国儿科人口中PCTH的发病率.
- 确定与PCTH相关的重大风险因素.
- 探索中国国内PCTH率的区域差异.
主要方法:
- 一项前性,多中心的队列研究,涉及8854名在中国15个中心接受结节切除术的儿科患者.
- 通过电子数据捕获 (EDC) 系统收集的数据超过17个月.
- 多变量逻辑回归分析用于确定手术后21天内PCTH的风险因素.
主要成果:
- PCTH的总发病率为1.99% (176名患者).
- 确定的危险因素包括异常凝血指标 (OR 10.56),更长的手术持续时间 (OR 1.02),术后咳 (OR 1.76) 和血液静止剂的使用 (OR 1.58),静脉注射抗生素 (OR 2.34) 和止痛药 (OR 2.33).
- 同时的腺切除术 (OR 0.35) 和半液体饮食 (OR 0.13) 与较低的出血率有关. 与中国北部相比,在中国东部,西南,中部和南部观察到较低的发病率.
结论:
- 结合性桃体切除术后的出血率与传统方法相比较.
- 凝血状态,手术持续时间和术后护理显著影响PCTH风险.
- 区域差异需要量身定制的管理策略,强调了结切除术在儿科护理中的安全性和有效性.
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