多不和脂肪酸的变化与高潮综合征患者的代谢综合征有关
Hua Ye1, Linju Zhou1, Qing Liu2
1Women's Health Department, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
概括
高水平的omega-6脂肪酸和低水平的omega-3脂肪酸与代谢综合征的危险因素有关,如高水平的甘油三和女性的腰与身高比,特别是绝经后的个体.
科学领域:
- 营养科学 营养科学
- 内分泌学 在内分泌学.
- 妇女健康 妇女健康
背景情况:
- 代谢综合征 (Mets) 对健康构成重大风险,特别是在高潮期间的女性中.
- 多不和脂肪酸 (PUFA),特别是欧米茄-6 (ω-6) 和欧米茄-3 (ω-3) 脂肪酸,在代谢健康中起着至关重要的作用.
- 了解PUFA比率与代谢综合征之间的关系对于预防策略至关重要.
研究的目的:
- 调查 ω-6 与 ω-3 多不和脂肪酸 (PUFA) 的比率与发生高潮综合征的女性代谢综合征的患病率之间的联系.
- 为了确定与关键代谢综合征指标相关的特定PUFA概况.
主要方法:
- 一组186名女性参与者接受了人体测量,血压评估和血脂,葡萄糖和胰岛素的血液分析.
- 血清PUFA水平,包括omega-3α-linolenic acid (ALA),omega-3 docosahexaenoic acid (DHA) 和omega-6 arachidonic acid (AA) 的含量,使用气色谱-质谱学量化.
- 参与者被分为绝经前期,有代谢综合征的绝经后期和没有代谢综合征的绝经后期.
主要成果:
- 患有代谢综合征的绝经后妇女表现出明显更高的腰围,腰比身高 (WHtR),血压,禁食葡萄糖,甘油三 (TG),LDL胆固醇,HbA1c和胰岛素水平.
- 在绝经前,绝经后有代谢综合征和绝经后没有代谢综合征的组中观察到血清中ALA,DHA,AA和ω-6/ω-3比的显著差异.
- 在代谢综合征组中观察到TG和WHtR升高.
结论:
- 高的 ω-6/ω-3比率和高的 ω-6 阿拉基酸,加上低的 ω-3 ALA 和 ω-3 DHA,与增加的甘油三和WHtR有关.
- 这些PUFA失衡有助于更高的代谢综合征的风险在绝经后妇女.
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