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解高 afinity 铜 (II) 复杂化由铁化剂deferasirox提供治疗和毒性洞察力

Aixa M Orta Rivera1, Luis A Landrau Correa2, Selene L Schiavone-Chamorro2

  • 1Department of Chemistry, University of Puerto Rico, Río Piedras Campus, Río Piedras, Puerto Rico, 00925-2537, United States.

ChemMedChem
|December 23, 2024
PubMed
概括

铁化剂deferasirox (Def) 显示出癌症治疗的潜力,但可能会产生副作用. 这项研究揭示了Def与铜 (Cu(II) 结合,形成表现出细胞毒性的稳定复合体,这表明了药物设计的新方向.

关键词:
癌症 癌症 癌症 癌症铜铜 铜铜 铜铜德弗拉西洛克斯是什么意思铁化剂是一种铁化剂.有毒性 有毒性

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