Runx3,Brn3a和Isl1的相互作用在自感神经元发育的早期阶段协调了转录程序

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Kira Orlovsky1, Elena Appel1, Shay Hantisteanu1

  • 1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

PLoS genetics
|December 23, 2024
PubMed
概括

Runx3转录因子通过与Brn3a和Isl1.1相互作用来调节TrkC神经元的发育. 这项研究解读了它们在通过发育神经元中的染色质可访问性来控制基因表达方面的合作.

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