1,2,4-Oxadiazole-5-Carboxylic 酸衍生物作为安全的种子处理纳米杀虫剂
Qi Zhang1, Dan Liu1, Yuqin Ou1
1State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
新的1,2,4-oxadiazole衍生物显示出强烈的杀菌活性. 化合物f1有效控制了大米白尖线虫 (Aphelenchoides besseyi),提供了一个有前途的安全种子处理替代品.
科学领域:
- 农业化学 农业化学
- 遗传学 遗传学 是一个学科.
- 有机合成 有机合成
背景情况:
- 植物寄生性线虫在全球显著降低作物产量.
- 开发新型,有效和安全的杀虫剂对于可持续农业至关重要.
研究的目的:
- 设计,合成和评估新型的1,2,4-oxadiazole-5-carboxylic 酸衍生物作为潜在的杀虫剂.
- 为了识别具有高效率的化合物对关键的植物寄生虫线虫物种.
主要方法:
- 通过基于活动的方法合成1,2,4-oxadiazole衍生物.
- 针对Meloidogyne incognita,Aphelenchoides besseyi和Bursaphelenchus xylophilus的生物测试. 这是一个非常好的方法.
- 在体外,半体内,和实验,以评估疗效和安全性.
主要成果:
- 几种合成的化合物显示出显著的杀菌性活性.
- 化合物f1对Aphelenchoides besseyi (LC50=19.0μg/mL) 呈现出优异的活性,表现优于商业性阴茎虫害.
- 化合物f1在子实验中证明了对大米种子的安全性.
结论:
- 化合物f1是一种高效的杀虫剂,用于对抗Aphelenchoides besseyi.
- 化合物f1具有多目标作用机制,包括皮膜损伤和酶抑制.
- 化合物f1显示出作为一种安全有效的种子处理杀虫剂的潜力,用于作物保护.
更多相关视频
08:22Author Spotlight: A New and Efficient Method for Comprehensive Metabolite Cytotoxicity Assessment of Triazole Pesticides in Plants
Published on: December 22, 2023
07:30A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
Published on: January 21, 2020
相关概念视频
Seed Structure and Early Development of the Sporophyte
Carboxylic Acids to Methylesters: Alkylation using Diazomethane
Nomenclature of Carboxylic Acid Derivatives: Amides and Nitriles
The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by...
Diazonium Group Substitution: –OH and –H
