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Updated: Jun 4, 2025

A Fluorescence-based Assay of Phospholipid Scramblase Activity
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TMEM63/OSCA家族的膜结构响应性脂质杂乱酶活性

Yugo Miyata1, Megumi Nishimura1, Aya Nagata1

  • 1Department of Medical Chemistry, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo, Japan.

FEBS letters
|December 23, 2024
PubMed
概括

脊椎动物TMEM63B的ortologs作为膜结构响应的scramblases,破坏了等离子膜的脂不对称性. 这种scramblase活性在物种之间保持,并与致病变异相关.

关键词:
离子通道 离子通道 离子通道机械传导 机械传导神经退行症的神经退行症脂酸是一种脂酸.血膜是一种等离子体膜.这就是Scramblase.

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