COVID-19:对呼吸系统的威胁
Ghulam Rasool1, Waqas Ahmed Khan2, Arif Muhammad Khan2
1Department of Allied Health Sciences, University of Sargodha, Sargodha, Punjab, Pakistan.
International journal of immunopathology and pharmacology
|December 23, 2024
概括
严重急性呼吸系统综合征冠状病毒-2 (SARS-CoV-2) 导致COVID-19,影响肺部,并可能导致慢性肺纤维化. 了解长期呼吸系统后果对于识别高风险幸存者至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 病理生理学 病理生理学
背景情况:
- 严重急性呼吸系统综合征冠状病毒-2 (SARS-CoV-2) 已经导致全球大流行,导致COVID-19.
- 众所周知,冠状病毒会对肺和心血管系统产生不利影响.
- 严重的COVID-19病例可以发展为急性呼吸困扰综合征 (ARDS),增加死亡风险.
研究的目的:
- 审查SARS-CoV-2对呼吸系统的影响.
- 探索ARDS相关并发症的机制,包括肺纤维化.
- 为了确定患有慢性肺纤维化风险的COVID-19幸存者.
主要方法:
- 关于SARS-CoV-2对呼吸系统组件的影响的文献综述.
- 对促进ARDS和肺纤维化机制的分析.
- 关于冠状病毒感染的长期后果信息的综合.
主要成果:
- SARS-CoV-2 感染会影响呼吸道,肺血管,肺膜,以及呼吸神经肌肉系统.
- 由SARS-CoV-2引起的细胞因子风暴主要准肺部,导致ARDS.
- 在COVID-19患者中观察到肺外表现和并发症.
结论:
- 进一步了解长期的冠状病毒感染后续是必不可少的.
- 确定COVID-19后患慢性肺纤维化风险的个体是一个优先事项.
- 本综述概述了严重的COVID-19肺纤维化的呼吸道并发症和潜在机制.
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