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卡尔莫杜林通过阻止TSC2-Rheb结合来增强mTORC1信号传递

Yuna Amemiya1, Yuichiro Ioi1, Makoto Araki2

  • 1Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan.

The Journal of biological chemistry
|December 24, 2024
PubMed
概括

离子 (Ca2+) 和calmodulin (CaM) 通过调节mTORC1通路来调节细胞生长. 这项研究揭示了Ca2+/CaM如何抑制TSC2与Rheb的结合,将Ca2+信号与mTORC1激活联系起来.

关键词:
在Rheb Rheb中,我们可以看到.和是最重要的.卡尔莫杜林是一种卡尔莫杜林.拉帕米辛复合物的机械性标1 1结核性硬化综合体 结核性硬化综合体

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