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用于解释临床预测模型的最受欢迎的XAI的基准测试:不值得信赖,但可能有用
Aida Brankovic1, David Cook2, Jessica Rahman1
1CSIRO Australian e-Health Research Centre, Brisbane, QLD, Australia.
对临床模型的可解释人工智能 (XAI) 方法由于不一致和适度一致的解释而缺乏可靠性. 这些人工智能工具可能提供见解,但不应该在没有批判性判断的情况下指导临床干预.
科学领域:
- 临床信息学 临床信息学
- 医疗保健中的人工智能
- 医疗决策支持 医疗决策支持
背景情况:
- 临床预测模型在医疗保健中越来越多地使用.
- 可解释的人工智能 (XAI) 旨在使临床医生能够理解这些模型.
- 在临床环境中评估XAI的可信度对于采用至关重要.
研究的目的:
- 评估临床预测模型的流行XAI方法的实用性和可靠性.
- 确定XAI解释是否与临床现实和工作流程保持一致.
主要方法:
- 使用来自澳大利亚医院的电子医疗记录 (EMR) 数据评估了两种常见的XAI方法.
- 评估了XAI解释的领域适当性,临床工作流的影响和一致性.
- 解释与实际的临床恶化触发因素进行了比较,并量化了一致性.
主要成果:
- XAI 方法显示违反了一致性标准.
- 在XAI解释和真正的临床触发因素之间发现了中等一致性 (0.47-0.8).
- 这些发现表明了可靠性和可操作性的问题,影响了临床医生的信任.
结论:
- 目前的XAI解释没有足够的可靠性来指导临床干预.
- XAI可能有助于模型故障排除,并提供额外的见解.
- 临床人员参与XAI开发和批判性判断对于安全实施至关重要.
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