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案例报告:一种新型的第三代抗CD19/CD22CART细胞结合自动HSCT治疗复发性伯基特淋巴瘤

Xiaodan Luo1, Ao Chen1, Le Qin2

  • 1The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

Frontiers in immunology
|December 24, 2024
PubMed
概括

这项研究提出了使用干细胞移植和CAR T细胞疗法治疗复发/耐药伯基特淋巴瘤 (BL) 的新疗法. 综合方法在患者身上实现了完全缓解,表明其潜在的有效性.

关键词:
用CAR T细胞疗法进行治疗.CD19/CD22的目标是双重目标.自主血型造血干细胞移植免疫疗法 免疫疗法复发/耐药的伯基特淋巴瘤

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.