改善HBV感染的年轻男性患者通过移动医疗保健平台定期跟踪的坚持,可能是降低晚期肝癌发病率的成本效益
Hao Liang1, Min Yang1, Dan Luo1
1Department of Hepatobiliary Surgery, Suining Central Hospital, Suining, Sichuan Province, People's Republic of China.
Patient preference and adherence
|December 24, 2024
概括
年轻人面临着升的肝癌率和高死亡率. 关键的危险因素包括男性性别,HBV感染和不良的医疗遵守,导致晚期诊断和低生存率.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 年轻成年人中肝癌发病率正在上升.
- 这一人口群体的肝癌死亡率很高.
- 年轻人是社会经济的重要贡献者,这使得这一趋势令人担忧.
研究的目的:
- 调查年轻患者肝癌相关的危险因素.
- 分析导致该群体晚期诊断和低生存率的因素.
- 确定改善年轻肝癌患者治疗结果的潜在策略.
主要方法:
- 追溯性研究设计.
- 分析了12年的患者数据.
- 多变量后勤回归用于识别独立的风险因素.
主要成果:
- 男性性别,乙型肝炎病毒 (HBV) 感染和家族病史是常见的危险因素.
- 乙型肝炎表面抗原 (HBsAg) 的阳性度很高 (78.3%).
- 55.7%被诊断为晚期肝癌,原因是医疗执法不良.
- 升高的阿斯巴酸氨基转移酶 (AST) 水平独立地与晚期疾病相关 (OR=4.262).
- 一年生存率非常低,为19.4%.
结论:
- 肝癌的高风险因素在年轻人中普遍存在.
- 对定期医疗检查的不充分遵守有助于先进的诊断.
- 低生存率强调了干预的紧迫性.
- 移动医疗保健和AST监测可以改善遵守和结果.
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