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Updated: May 8, 2025

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设计,合成,生物评估和分子对接研究新型1,3,4-亚二醇基化合物作为EGFR抑制剂

Marwa I Serag1, Samar S Tawfik1,2, Hassan M Eisa1

  • 1Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Drug development research
|December 24, 2024
PubMed
概括

新的1,3,4-thiadiazole混合物显示出强大的抗癌活性. 化合物9a有效抑制癌细胞中的表皮生长因子受体 (EGFR),诱导细胞亡和细胞循环停止,对正常细胞的毒性最小.

关键词:
在 EGFR 基因酶.它具有抗癌活性,具有抗癌活性.停靠研究对接研究.这种药物是提亚迪亚 (thiadiazole)

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