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多发性硬化症的发病表现在西班牙裔/拉丁裔美国人与非西班牙裔白人美国人相比有所不同

Farren Bs Briggs¹, Devon S Conway², Carrie M Hersh³

¹Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.

Multiple sclerosis (Houndmills, Basingstoke, England)

|December 24, 2024

概括

与非西班牙裔白人相比,患有多发性硬化症 (MS) 的西班牙裔/拉丁裔个人表现出不同的表现模式. 具体来说,西班牙裔/拉丁裔其他 (HLO) 患者在发病时年龄较早,在初始诊断时患上渐进性多发性硬化症的可能性更高.

科学领域:

神经学神经学
流行病学流行病学
健康差异在健康上的差异

背景情况:

在西班牙裔/拉丁裔 (HL) 人群中对多发性硬化症 (MS) 呈现的理解有限.
需要比较HL和非西班牙裔白人 (NHW) 患有MS (pwMS) 的人之间的临床特征.

研究的目的:

为了比较HL和NHW pwMS的发病年龄 (AAO) 和最初的疾病严重程度.
调查多发性硬化症呈现的种族差异.

主要方法:

在七个美国学术医疗中心使用MS PATHS注册表进行横截面研究.
HL种群分为HL白色 (HLW) 和HL其他 (HLO).
多变量模型分析了民族种族变量,AAO,并呈现疾病过程,重点关注1970年以后出生的人.

主要成果:

与NHW pwMS相比,西班牙裔/拉丁裔其他 (HLO) pwMS表现出较早的AAO和更高的发病率.
在所有HL pwMS中,AAO并没有根据性别或最初的疾病过程 (复发与进展) 不同.
在年轻的HLO成年人 (1970年或之后出生) 中,发病时进展性MS与复发性MS相比较早的AAO有关.

结论:

与NHW个人相比,HL患者的多发性硬化症呈现方式存在显著差异.
这些发现强调了在MS的表现和管理中考虑种族因素的重要性.

关键词:

西班牙裔西班牙裔.拉丁裔拉丁裔是什么意思拉丁语x 拉丁语x 拉丁语x 发病时的年龄在开始时.疾病的发展过程.多发性硬化症多发性硬化症

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