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Luiz Henrique Alves Guerra¹, Nayara Fernanda da Costa Castro¹, Fernanda Costa Jubilato¹

¹Department of Biological Sciences, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (UNESP), São José do Rio Preto, São Paulo, Brazil.

|December 24, 2024

概括

在老化过程中摄入子油可以通过减少前列腺重量,炎症和BPH标志物来减轻Gerbils的前列腺问题. 这种天然化合物支持前列腺健康,并对抗与年龄相关的衰退.

科学领域:

老年学是一门学科.
内分泌学在内分泌学.
自然产品研究自然产品研究

背景情况:

良性前列腺增生症 (BPH) 与衰老期间的荷尔蒙失衡有关.
草药正在探索作为BPH的补充治疗方法.
已知子油有可能干扰丸激素诱导的BPH,但其在衰老过程中的影响尚未研究.

研究的目的:

为了评估子油摄入量对老化大鼠前列腺的影响.
为了研究子油对与年龄相关的前列腺变化的影响.

主要方法:

用水 (对照组) 或子油食大鼠1年.
测量了血清激素水平 (,雌激素).
分析了前列腺组织病理,细胞增殖 (PHH3),细胞亡 (TUNEL) 和激素受体表达 (AR,ERα,ERβ).

主要成果:

子油组显示前列腺体重,肌体厚度以及雄激素和雌激素受体的表达减少.
子油摄入量降低了BPH和内皮瘤的发生率.
前列腺细胞亡增加,与年龄相关的变化减轻.

结论:

在整个衰老过程中,子油的消费抵消了与年龄相关的对前列腺健康的有害影响.
这项研究表明子油是维持老龄人口前列腺健康的潜在治疗剂.

关键词:

衰老的衰老衰老的衰老子油是指子油中的一种.前列腺前列腺前列腺前列腺增生症前列腺增生症

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