在"女性机构间艾滋病毒研究"中,认知个体内变异性是否预测了艾滋病毒感染和没有艾滋病毒感染的女性日常功能表现的变化?
David E Vance1, Yanxun Xu2,3, Raha Dastgheyb4
1School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Applied neuropsychology. Adult
|December 24, 2024
概括
认知个体内变异性 (IIV) 预测了艾滋病毒感染女性 (WWH) 的功能障碍. 不同的IIV测量显示出不同的预测能力,变化系数 (covIIV) 对WWH特别有影响.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 认知个体内变化 (IIV) 是神经病理学的新兴指标.
- 了解IIV对日常功能的影响对于管理HIV等健康状况至关重要.
研究的目的:
- 研究艾滋病毒感染妇女 (WWH) 与没有艾滋病毒感染妇女 (WWoH) 之间的认知IIV和日常功能之间的关联.
- 为了确定认知IIV (sdIIV和covIIV) 的不同测量是否对功能结果具有不同的预测价值.
主要方法:
- 在7个领域和日常生活工具活动 (IADL) 中评估认知表现,使用Lawton & Brody尺度在1086个WWH和494个WWoH.
- 计算了两种类型的认知IIV:标准偏差 (sdIIV) 和变化系数 (covIIV).
- 采用了通用线性混合效应模型来分析认知IIV测量和IADL项目得分之间的关联,按艾滋病毒状况和病毒抑制分层.
主要成果:
- 认知IIV (sdIIV和covIIV) 在WWoH中与IADL表现无关.
- sdIIV和covIIV都与IADL在第一次世界大战中的功能较差和病毒抑制的第二次世界大战有关.
- 在CovIIV测量预测较差的功能性能在两倍多的IADL项目 (10),相比 sdIIV (5) 在世界大战.
结论:
- 认知IIV是WWH中功能障碍的重要预测因素.
- 用于计算认知IIV的方法影响其对功能结果的预测能力,covIIV显示出更大的影响.
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