对感染性内心炎的预后和手术益处的多变量和生存分析
Tian Xu Song1, Yao Dong Sun1, Bufan Zhang1
1Department of Cardiovascular Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Scandinavian cardiovascular journal : SCJ
|December 24, 2024
概括
手术干预改善了感染性内心炎 (IE) 患者的结果. 周环瘤和心脏功能不佳预测短期的预后不佳,而脑梗塞和心脏功能不佳预测长期的死亡率.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 手术干预 手术干预
背景情况:
- 感染性内心炎 (IE) 治疗依赖于抗生素,但许多患者需要手术.
- 对于IE的外科干预具有重大风险.
- 预测IE预后不佳的预测因素,特别是围腹,需要进一步澄清.
研究的目的:
- 确定感染性内心炎 (IE) 中不良结果的预测因素.
- 评估手术干预对IE患者预后的影响.
- 提高对影响IE预后的因素的理解.
主要方法:
- 210名IE患者的回顾性队列研究 (2016年12月 - 2023年6月).
- 人口统计学,心声学,实验室和手术数据的比较,对结果差和良好的患者进行比较.
- 评估短期结果和长期存活率通过追踪到2024年6月.
主要成果:
- 手术治疗与更好的短期预后 (OR 0.211) 和改善的长期生存率 (HR 0.200) 相关联.
- 周环 (OR 4.948) 和心脏功能差 (NYHA II/III) 预测短期预后不佳.
- 大脑梗塞 (HR 1.939) 和心脏功能差 (NYHA II/III) 预测了长期死亡率的增加.
结论:
- 手术治疗与感染性内心炎 (IE) 患者的短期和长期结果的改善有关.
- 周环腹和心脏功能受损是关键的短期预后因素.
- 脑梗塞和心脏功能受损是显著的长期死亡预测因素.
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