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案例332:氨酸激酶抑制剂诱导的肠道淋巴切除症

Cameron Adler¹, Christine Menias¹

¹From the Department of Radiology, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054.

|December 24, 2024

概括

本案例研究详细介绍了一名患有复发性类细胞癌的患者,该患者接受了pazopanib和立体辐射治疗. 监测成像显示,尽管接受治疗,疾病仍在进展.

科学领域:

在瘤学瘤学.
医疗成像医学成像

背景情况:

一名65岁的男性,有类细胞癌史,先前进行切除术,出现了复发性疾病.
患者接受了最大剂量帕佐帕尼布和息性立体性身体辐射疗法 (SBRT).

研究的目的:

报告患有复发性细胞癌的患者的临床过程和成像发现.
在接受全身疗法和放射治疗的患者中记录治疗反应和不良事件.

主要方法:

患者在开始服用帕佐帕尼布7个月后,并在完成SBRT后不久进行了监控成像 (对比度增强CT).
进行了实验室检测,包括完整血清和综合代谢面板.

主要成果:

监测成像显示了下腔静脉旁边的复发性疾病.
患者出现了需要洛佩拉治疗的腹,血清总蛋白质低,性酸酶升高.
生命体征和白细胞数量保持正常.

结论:

这一案例凸显了治疗复发性细胞癌的挑战.
需要进一步研究治疗疗效和副作用的管理.

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