为什么有用性很少是有用的
Fangyi Wang1, Mitchell J Feldmann1, Daniel E Runcie1
1Department of Plant Sciences, University of California Davis, Davis, CA 95616, USA.
G3 (Bethesda, Md.)
|December 24, 2024
概括
精确的计算分期可以帮助预测后代的特征在繁殖计划. 然而,使用实用性标准比预测家庭平均值的好处很小,即使准确度很高.
科学领域:
- 植物育种 植物育种
- 定量遗传学 是一种定量遗传学.
- 基因组选择 基因组选择
背景情况:
- 伴侣选择对于有效的繁殖计划至关重要.
- 实用性标准通过考虑后代的平均值和标准偏差来增强伴侣选择.
- 预测后代的标准偏差是具有挑战性的,因为等位基因相位要求.
研究的目的:
- 从未分相的基因型数据开发一种估计分相精度的方法.
- 评估分阶段精度是否足以预测家族标准偏差.
- 评估可准确预测有用性标准的条件.
主要方法:
- 开发了一种使用未分相基因型数据估计分相精度的方法.
- 利用不同基因架构的模拟.
- 将该方法应用于真正的草繁殖群体.
主要成果:
- 高精度的计算分期使得家庭标准偏差的预测成为可能.
- 实用性标准仅在特定条件下提供比预测家庭平均值更好的优势:高选择强度,高遗传性和少数定量特征位点 (QTL).
- 使用家庭实用性的整体收益是边际的.
结论:
- 精确的分阶段是可行的,但在伴侣选择方面提供了有限的优势.
- 实用性标准的实际实用性受到特定的遗传和选择参数的限制.
- 由于收益很小,未来的育种策略可能不会从这个标准中显著受益.
相关概念视频
The Availability Heuristic
5.9K
A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):
5.9K
Heuristics
74
Heuristics are problem-solving strategies that use mental shortcuts to simplify decision-making. Unlike algorithms, which must be followed precisely to achieve a correct result, heuristics offer a general problem-solving framework. They save time and energy but can sometimes lead to less rational decisions.
People often rely on heuristics when faced with an overload of information, limited time, low importance of the decision, limited information, or when a heuristic readily comes to mind. For...
People often rely on heuristics when faced with an overload of information, limited time, low importance of the decision, limited information, or when a heuristic readily comes to mind. For...
74
Dose-Response Relationship: Potency and Efficacy
4.2K
The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it...
4.2K
Buffer Effectiveness
48.5K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
The buffer capacity is the amount of acid or base that can be added to a given volume...
48.5K
Naturalistic Observations
15.4K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
15.4K
Efficiency of The Carnot Cycle
2.5K
The hypothetical Carnot cycle consists of an ideal gas subjected to two isothermal and two adiabatic processes. Since the internal energy of an ideal gas depends only on its temperature, which is the same before and after the completion of the Carnot cycle, there is no change in its internal energy. Hence, using the first law of thermodynamics, the total heat exchanged by the ideal gas equals the total work done. Thus, we can quantify the efficiency of the Carnot cycle via the heat exchanged...
2.5K


